| 22. Round | 04/02/2021 | Mantova 1911 SSD | - | Calcio Padova | 0:6 |  |
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| 23. Round | 07/02/2021 | AC Perugia Calcio | - | Mantova 1911 SSD | 4:2 |  |
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| 24. Round | 14/02/2021 | Mantova 1911 SSD | - | Sambenedettese | 1:1 | ||||
| 25. Round | 18/02/2021 | Matelica | - | Mantova 1911 SSD | 0:0 | ||||
| 26. Round | 21/02/2021 | Mantova 1911 SSD | - | Alma Juventus Fano | 0:2 | |
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| 27. Round | 27/02/2021 | Imolese Calcio | - | Mantova 1911 SSD | 1:5 | |
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| 28. Round | 03/03/2021 | US Arezzo | - | Mantova 1911 SSD | 1:1 | |
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| 29. Round | 08/03/2021 | Mantova 1911 SSD | - | FC Südtirol | 1:1 |
Italy