| 1. Round | 15/08/2021 | FC Barcelona | - | Real Sociedad | 4:2 |  |
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| 2. Round | 21/08/2021 | Athletic Club | - | FC Barcelona | 1:1 | ||||
| 3. Round | 29/08/2021 | FC Barcelona | - | Getafe CF | 2:1 | |
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| 5. Round | 20/09/2021 | FC Barcelona | - | Granada CF | 1:1 | ||||
| 6. Round | 23/09/2021 | Cádiz CF | - | FC Barcelona | 0:0 |  |
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| 8. Round | 02/10/2021 | Atlético Madrid | - | FC Barcelona | 2:0 | ||||
| 9. Round | 17/10/2021 | FC Barcelona | - | Valencia CF | 3:1 | ||||
| 10. Round | 24/10/2021 | FC Barcelona | - | Real Madrid | 1:2 | ||||
| 11. Round | 27/10/2021 | Rayo Vallecano | - | FC Barcelona | 1:0 |
Spain
