| 1. Round | 21/09/2020 | Torino FC [Youth] | - | Lazio Roma [Youth] | 2:3 |  |
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| 2. Round | 27/09/2020 | Sampdoria [Youth] | - | Lazio Roma [Youth] | 1:1 | ||||
| 3. Round | 04/10/2020 | Lazio Roma [Youth] | - | Bologna FC [Youth] | 3:3 |  |
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| 4. Round | 18/10/2020 | Sassuolo Calcio [Youth] | - | Lazio Roma [Youth] | 2:2 | ||||
| 6. Round | 30/10/2020 | ACF Fiorentina [Youth] | - | Lazio Roma [Youth] | 1:3 | ||||
| 7. Round | 23/01/2021 | Lazio Roma [Youth] | - | AC Milan [Youth] | 0:3 | ||||
| 8. Round | 30/01/2021 | Juventus [Youth] | - | Lazio Roma [Youth] | 2:0 | ||||
| 9. Round | 10/02/2021 | Lazio Roma [Youth] | - | Empoli FC [Youth] | 2:6 | ||||
| 20. Round | 24/04/2021 | AS Roma [Youth] | - | Lazio Roma [Youth] | 1:1 | ||||
| 21. Round | 03/05/2021 | Lazio Roma [Youth] | - | ACF Fiorentina [Youth] | 5:0 | |
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| 22. Round | 08/05/2021 | AC Milan [Youth] | - | Lazio Roma [Youth] | 2:1 | ||||
| 18. Round | 12/05/2021 | Bologna FC [Youth] | - | Lazio Roma [Youth] | 2:1 | ||||
| 24. Round | 22/05/2021 | Empoli FC [Youth] | - | Lazio Roma [Youth] | 3:0 |
Netherlands
Suriname