| 3. Round | 24/08/2018 | Olympique Lyonnais | - | RC Strasbourg | 2:0 | ||||
| 8. Round | 29/09/2018 | RC Strasbourg | - | Dijon FCO | 3:0 | ||||
| 13. Round | 09/11/2018 | Lille OSC | - | RC Strasbourg | 0:0 | ||||
| 14. Round | 24/11/2018 | RC Strasbourg | - | Nîmes Olympique | 0:1 | ||||
| 16. Round | 05/12/2018 | RC Strasbourg | - | Paris Saint-Germain | 1:1 | ||||
| 20. Round | 13/01/2019 | Toulouse FC | - | RC Strasbourg | 1:2 | ||||
| 21. Round | 19/01/2019 | AS Monaco | - | RC Strasbourg | 1:5 |  |
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| 22. Round | 26/01/2019 | RC Strasbourg | - | Girondins Bordeaux | 1:0 | ||||
| 23. Round | 13/02/2019 | AS Saint-Étienne | - | RC Strasbourg | 2:1 | ||||
| 25. Round | 17/02/2019 | SM Caen | - | RC Strasbourg | 0:0 | ||||
| 26. Round | 22/02/2019 | RC Strasbourg | - | Lille OSC | 1:1 | ||||
| 28. Round | 09/03/2019 | RC Strasbourg | - | Olympique Lyonnais | 2:2 | ||||
| 29. Round | 16/03/2019 | Nîmes Olympique | - | RC Strasbourg | 2:2 | |
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| 30. Round | 03/04/2019 | RC Strasbourg | - | Stade de Reims | 4:0 | ||||
| 32. Round | 13/04/2019 | RC Strasbourg | - | EA Guingamp | 3:3 | ||||
| 35. Round | 03/05/2019 | RC Strasbourg | - | Olympique Marseille | 1:1 | ||||
| 36. Round | 11/05/2019 | Dijon FCO | - | RC Strasbourg | 2:1 |
France
Mali 