Championship   M. W D L goals
  at home 27 12 8 7 45 : 32
  Away 27 7 8 12 28 : 49
  54 19 16 19 73 : 81
League Cup   M. W D L goals
  at home 1 1 0 0 4 : 3
  1 1 0 0 4 : 3
League One   M. W D L goals
  at home 1 0 0 1 0 : 1
  Away 1 1 0 0 3 : 1
  2 1 0 1 3 : 2
overall   M. W D L goals
  at home 29 13 8 8 49 : 36
  Away 28 8 8 12 31 : 50
  Neutral Place 0 0 0 0 0 : 0
  57 21 16 20 80 : 86
Championship
2023/2024 25. Round Southampton FC - Plymouth Argyle 2:1 (0:0)
2023/2024 3. Round Plymouth Argyle - Southampton FC 1:2 (0:0)
2008/2009 25. Round Plymouth Argyle - Southampton FC 2:0 (1:0)
2008/2009 19. Round Southampton FC - Plymouth Argyle 0:0 (0:0)
2007/2008 33. Round Southampton FC - Plymouth Argyle 0:2 (0:2)
2007/2008 28. Round Plymouth Argyle - Southampton FC 1:1 (0:1)
2006/2007 27. Round Plymouth Argyle - Southampton FC 1:1 (0:1)
2006/2007 8. Round Southampton FC - Plymouth Argyle 1:0 (0:0)
2005/2006 31. Round Plymouth Argyle - Southampton FC 2:1 (1:0)
2005/2006 10. Round Southampton FC - Plymouth Argyle 0:0 (0:0)
1976/1977 9. Round Southampton FC - Plymouth Argyle 4:1
1976/1977 5. Round Plymouth Argyle - Southampton FC 1:1
1975/1976 9. Round Plymouth Argyle - Southampton FC 1:0
1975/1976 1. Round Southampton FC - Plymouth Argyle 1:0
1965/1966 10. Round Plymouth Argyle - Southampton FC 2:3
1965/1966 5. Round Southampton FC - Plymouth Argyle 4:1
1964/1965 7. Round Plymouth Argyle - Southampton FC 4:0
1964/1965 5. Round Southampton FC - Plymouth Argyle 5:0
1963/1964 5. Round Plymouth Argyle - Southampton FC 1:1
1963/1964 5. Round Southampton FC - Plymouth Argyle 1:2
1962/1963 8. Round Southampton FC - Plymouth Argyle 1:1
1962/1963 8. Round Plymouth Argyle - Southampton FC 2:1
1961/1962 5. Round Plymouth Argyle - Southampton FC 4:0
1961/1962 1. Round Southampton FC - Plymouth Argyle 1:2
1960/1961 8. Round Southampton FC - Plymouth Argyle 1:1
1960/1961 3. Round Plymouth Argyle - Southampton FC 1:3
1952/1953 2. Round Plymouth Argyle - Southampton FC 3:1
1952/1953 1. Round Southampton FC - Plymouth Argyle 2:3
1949/1950 9. Round Plymouth Argyle - Southampton FC 0:0
1949/1950 4. Round Southampton FC - Plymouth Argyle 3:3
1948/1949 2. Round Southampton FC - Plymouth Argyle 2:0
1948/1949 1. Round Plymouth Argyle - Southampton FC 1:2
1947/1948 9. Round Southampton FC - Plymouth Argyle 2:3
1947/1948 4. Round Plymouth Argyle - Southampton FC 3:1
1946/1947 8. Round Plymouth Argyle - Southampton FC 2:3
1946/1947 3. Round Southampton FC - Plymouth Argyle 5:1
1938/1939 10. Round Plymouth Argyle - Southampton FC 2:0
1938/1939 2. Round Southampton FC - Plymouth Argyle 2:1
1937/1938 10. Round Plymouth Argyle - Southampton FC 4:0
1937/1938 2. Round Southampton FC - Plymouth Argyle 0:0
1936/1937 8. Round Southampton FC - Plymouth Argyle 0:0
1936/1937 8. Round Plymouth Argyle - Southampton FC 3:1
1935/1936 9. Round Southampton FC - Plymouth Argyle 2:0
1935/1936 4. Round Plymouth Argyle - Southampton FC 0:0
1934/1935 8. Round Southampton FC - Plymouth Argyle 1:0
1934/1935 4. Round Plymouth Argyle - Southampton FC 4:0
1933/1934 8. Round Plymouth Argyle - Southampton FC 0:0
1933/1934 4. Round Southampton FC - Plymouth Argyle 0:1
1932/1933 9. Round Southampton FC - Plymouth Argyle 2:0
1932/1933 4. Round Plymouth Argyle - Southampton FC 1:1
1931/1932 9. Round Plymouth Argyle - Southampton FC 1:2
1931/1932 5. Round Southampton FC - Plymouth Argyle 0:6
1930/1931 6. Round Southampton FC - Plymouth Argyle 3:3
1930/1931 2. Round Plymouth Argyle - Southampton FC 2:3
League Cup
1966/1967 2. Round Southampton FC - Plymouth Argyle 4:3
League One
2010/2011 39. Round Plymouth Argyle - Southampton FC 1:3 (0:1)
2010/2011 1. Round Southampton FC - Plymouth Argyle 0:1 (0:0)

For games that were decided on penalties the score after 120 minutes will be included in the ranking