| 3. Round | 08/05/2022 | US Triestina | - | Palermo FC | 1:2 | ||||
| Quarter-finals | 17/05/2022 | Virtus Entella | - | Palermo FC | 1:2 | ||||
| Quarter-finals | 21/05/2022 | Palermo FC | - | Virtus Entella | 2:2 | ||||
| Semi-finals | 25/05/2022 | Feralpisalò | - | Palermo FC | 0:3 | ||||
| Final | 05/06/2022 | Calcio Padova | - | Palermo FC | 0:1 |  |
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| Final | 12/06/2022 | Palermo FC | - | Calcio Padova | 1:0 |
France