| 1. Round | 21/08/2021 | Sportfreunde Baumberg | - | 1. FC Bocholt | 0:3 | ||||
| 2. Round | 27/08/2021 | SSVg Velbert | - | Sportfreunde Baumberg | 6:2 | ||||
| 3. Round | 05/09/2021 | Sportfreunde Baumberg | - | TVD Velbert | 0:1 | ||||
| 4. Round | 07/10/2021 | SpVgg Sterkrade-Nord | - | Sportfreunde Baumberg | 1:5 | ||||
| 5. Round | 27/10/2021 | Sportfreunde Baumberg | - | Schwarz-Weiß Essen | 3:0 | ||||
| 11. Round | 31/10/2021 | Sportfreunde Baumberg | - | 1. FC Mönchengladbach | 2:0 | ||||
| 12. Round | 07/11/2021 | FSV Duisburg | - | Sportfreunde Baumberg | 0:1 | ||||
| 6. Round | 10/11/2021 | FC Kray | - | Sportfreunde Baumberg | 0:3 | ||||
| 13. Round | 14/11/2021 | Sportfreunde Baumberg | - | VfB 03 Hilden | 1:2 |  |
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| 14. Round | 27/11/2021 | SC Velbert | - | Sportfreunde Baumberg | 0:3 | ||||
| 16. Round | 12/12/2021 | TV Jahn Hiesfeld | - | Sportfreunde Baumberg | 2:3 | ||||
| 18. Round | 20/02/2022 | Cronenberger SC | - | Sportfreunde Baumberg | 1:3 | ||||
| 20. Round | 06/03/2022 | SC Düsseldorf-West | - | Sportfreunde Baumberg | 0:3 | ||||
| 22. Round | 20/03/2022 | Sportfreunde Baumberg | - | 1. FC Kleve | 2:1 | ||||
| 23. Round | 27/03/2022 | TSV Meerbusch | - | Sportfreunde Baumberg | 1:6 |
Germany