| 2. Round | 18/02/2010 | Villarreal CF | - | VfL Wolfsburg | 2:2 | ||||
| 2. Round | 25/02/2010 | VfL Wolfsburg | - | Villarreal CF | 4:1 | ||||
| Round of 16 | 11/03/2010 | Rubin Kazan | - | VfL Wolfsburg | 1:1 | ||||
| Round of 16 | 18/03/2010 | VfL Wolfsburg | - | Rubin Kazan | 2:1 aet | ||||
| Quarter-finals | 01/04/2010 | Fulham FC | - | VfL Wolfsburg | 2:1 |  |
 |
Germany