| 1. Round | 29/08/2021 | SG Wattenscheid 09 | - | RSV Meinerzhagen | 3:2 |  |
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| 2. Round | 03/09/2021 | RSV Meinerzhagen | - | FCE Rheine | 1:2 | ||||
| 3. Round | 12/09/2021 | TSG Sprockhövel | - | RSV Meinerzhagen | 6:1 | ||||
| 4. Round | 19/09/2021 | RSV Meinerzhagen | - | Hammer SpVg | 2:0 | ||||
| 5. Round | 26/09/2021 | Sportfreunde Siegen | - | RSV Meinerzhagen | 3:1 | ||||
| 7. Round | 10/10/2021 | FC Gütersloh | - | RSV Meinerzhagen | 3:0 | ||||
| 8. Round | 17/10/2021 | RSV Meinerzhagen | - | TuS Haltern | 2:3 | ||||
| 17. Round | 20/02/2022 | RSV Meinerzhagen | - | SG Finnentrop/Bamenohl | 2:4 | ||||
| 18. Round | 06/03/2022 | 1. FC Kaan-Marienborn | - | RSV Meinerzhagen | 1:0 | ||||
| 21. Round | 27/03/2022 | RSV Meinerzhagen | - | SV Schermbeck | 0:1 | ||||
| 19. Round | 31/03/2022 | RSV Meinerzhagen | - | Viktoria Clarholz | 0:0 | ||||
| 20. Round | 07/04/2022 | TuS Ennepetal | - | RSV Meinerzhagen | 0:3 |
Turkey