| 2. Round | 27/09/2020 | Türkgücü München | - | 1. FC Kaiserslautern | 3:0 | ||||
| 19. Round | 16/01/2021 | SC Verl | - | 1. FC Kaiserslautern | 1:1 | ||||
| 22. Round | 30/01/2021 | 1. FC Kaiserslautern | - | SV Wehen Wiesbaden | 0:1 | ||||
| 25. Round | 20/02/2021 | FC Ingolstadt 04 | - | 1. FC Kaiserslautern | 1:0 |  |
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| 26. Round | 27/02/2021 | 1. FC Kaiserslautern | - | SV Meppen | 2:2 | ||||
| 27. Round | 06/03/2021 | Hansa Rostock | - | 1. FC Kaiserslautern | 2:1 | |
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| 28. Round | 07/04/2021 | 1. FC Kaiserslautern | - | FSV Zwickau | 2:2 | ||||
| 31. Round | 10/04/2021 | VfB Lübeck | - | 1. FC Kaiserslautern | 1:1 | ||||
| 32. Round | 17/04/2021 | 1. FC Kaiserslautern | - | 1. FC Saarbrücken | 2:1 | ||||
| 33. Round | 20/04/2021 | MSV Duisburg | - | 1. FC Kaiserslautern | 2:2 | |
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| 34. Round | 24/04/2021 | 1. FC Kaiserslautern | - | SpVgg Unterhaching | 3:2 | ||||
| 35. Round | 04/05/2021 | TSV 1860 München | - | 1. FC Kaiserslautern | 3:0 | ||||
| 38. Round | 22/05/2021 | 1. FC Kaiserslautern | - | SC Verl | 1:1 |
Germany