| 1. Round | 30/08/1980 | BSG Stahl Nordwest Leipzig | - | BSG Stahl Thale | 1:0 | ||||
| 2. Round | 06/09/1980 | BSG Stahl Thale | - | ASG Vorwärts Dessau | 5:1 |  |
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| 3. Round | 13/09/1980 | BSG Chemie Leipzig | - | BSG Stahl Thale | 0:0 | ||||
| 4. Round | 20/09/1980 | BSG Chemie Wolfen | - | BSG Stahl Thale | 0:1 | |
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| 5. Round | 04/10/1980 | BSG Stahl Thale | - | SG Dynamo Eisleben | 3:1 | |
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| 6. Round | 07/10/1980 | BSG Chemie Buna Schkopau | - | BSG Stahl Thale | 1:1 | |
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| 7. Round | 19/10/1980 | BSG Stahl Thale | - | BSG Lokomotive Stendal | 3:0 | ||||
| 8. Round | 26/10/1980 | BSG Chemie Zeitz | - | BSG Stahl Thale | 1:4 | |
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| 9. Round | 08/11/1980 | BSG Stahl Thale | - | BSG Stahl Blankenburg | 1:1 | ||||
| 10. Round | 15/11/1980 | BSG MK Sangerhausen | - | BSG Stahl Thale | 1:1 | ||||
| 11. Round | 22/11/1980 | BSG Stahl Thale | - | Chemie Schönebeck | 1:0 | ||||
| 13. Round | 06/12/1980 | ASG Vorwärts Dessau | - | BSG Stahl Thale | 4:0 | ||||
| 14. Round | 12/12/1980 | BSG Stahl Thale | - | BSG Chemie Leipzig | 0:1 |
Germany