| 19. Round | 28/03/1981 | Hansa Rostock | - | FC Karl-Marx-Stadt | 1:1 | ||||
| 20. Round | 11/04/1981 | FC Karl-Marx-Stadt | - | BSG Chemie Böhlen | 2:1 | ||||
| 21. Round | 15/04/1981 | BFC Dynamo | - | FC Karl-Marx-Stadt | 5:0 | ||||
| 22. Round | 25/04/1981 | FC Karl-Marx-Stadt | - | BSG Stahl Riesa | 5:4 |  |
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| 23. Round | 09/05/1981 | FC Carl Zeiss Jena | - | FC Karl-Marx-Stadt | 5:0 | ||||
| 24. Round | 16/05/1981 | FC Karl-Marx-Stadt | - | HFC Chemie | 2:2 | ||||
| 25. Round | 23/05/1981 | BSG Sachsenring Zwickau | - | FC Karl-Marx-Stadt | 1:0 | ||||
| 26. Round | 30/05/1981 | FC Karl-Marx-Stadt | - | 1. FC Lokomotive Leipzig | 6:1 |
Germany