| 21. Round | 31/01/2016 | Rot-Weiss Essen | - | 1. FC Köln II | 0:0 | ||||
| 22. Round | 06/02/2016 | SV Rödinghausen | - | Rot-Weiss Essen | 0:0 | ||||
| 25. Round | 26/02/2016 | Rot-Weiss Essen | - | SG Wattenscheid 09 | 2:2 |  |
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| 28. Round | 11/03/2016 | Rot-Weiss Essen | - | Bor. Mönchengladbach II | 3:3 | ||||
| 29. Round | 19/03/2016 | Fortuna Düsseldorf II | - | Rot-Weiss Essen | 1:0 | ||||
| 30. Round | 24/03/2016 | Rot-Weiss Essen | - | SC Verl | 1:0 | ||||
| 31. Round | 28/03/2016 | Viktoria Köln | - | Rot-Weiss Essen | 1:0 |  |
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| 32. Round | 02/04/2016 | Rot-Weiss Essen | - | Sportfreunde Lotte | 0:2 | ||||
| 33. Round | 08/04/2016 | Rot Weiss Ahlen | - | Rot-Weiss Essen | 1:2 | ||||
| 24. Round | 12/04/2016 | TuS Erndtebrück | - | Rot-Weiss Essen | 1:0 | ||||
| 35. Round | 23/04/2016 | FC Schalke 04 II | - | Rot-Weiss Essen | 0:0 | ||||
| 27. Round | 27/04/2016 | Rot-Weiss Essen | - | SSVg Velbert | 3:2 | ||||
| 36. Round | 07/05/2016 | Rot-Weiss Essen | - | Rot-Weiß Oberhausen | 0:2 | ||||
| 37. Round | 14/05/2016 | FC Kray | - | Rot-Weiss Essen | 2:3 | ||||
| 38. Round | 21/05/2016 | Rot-Weiss Essen | - | Borussia Dortmund II | 2:1 |
Romania
Germany