| 2. Round | 14/04/2022 | Holzwickeder SC | - | TuS Haltern | 1:2 | ||||
| 3. Round | 18/04/2022 | RSV Meinerzhagen | - | Holzwickeder SC | 1:3 |  |
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| 4. Round | 24/04/2022 | Holzwickeder SC | - | TSG Sprockhövel | 0:1 | ||||
| 6. Round | 05/05/2022 | Hammer SpVg | - | Holzwickeder SC | 3:3 | ||||
| 7. Round | 08/05/2022 | Holzwickeder SC | - | Viktoria Clarholz | 2:1 | ||||
| 8. Round | 15/05/2022 | Westfalia Herne | - | Holzwickeder SC | 0:2 | |
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| 1. Round | 19/05/2022 | SpVgg Vreden | - | Holzwickeder SC | 3:2 | ||||
| 11. Round | 06/06/2022 | Holzwickeder SC | - | SG Finnentrop/Bamenohl | 3:1 | |
Germany