| 3. Round | 06/08/2017 | Union Fürstenwalde | - | 1. FC Lok Leipzig | 0:2 | ||||
| 4. Round | 19/08/2017 | 1. FC Lok Leipzig | - | FSV 63 Luckenwalde | 4:2 | ||||
| 6. Round | 09/09/2017 | 1. FC Lok Leipzig | - | FC Viktoria 1889 Berlin | 0:1 | ||||
| 8. Round | 22/09/2017 | 1. FC Lok Leipzig | - | FC Oberlausitz | 3:0 | ||||
| 10. Round | 03/10/2017 | 1. FC Lok Leipzig | - | Energie Cottbus | 0:0 | ||||
| 11. Round | 15/10/2017 | FSV Budissa Bautzen | - | 1. FC Lok Leipzig | 0:0 | ||||
| 12. Round | 22/10/2017 | 1. FC Lok Leipzig | - | VfB Auerbach | 1:1 | ||||
| 14. Round | 05/11/2017 | 1. FC Lok Leipzig | - | Germania Halberstadt | 2:1 |  |
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| 16. Round | 13/12/2017 | 1. FC Lok Leipzig | - | Berliner AK 07 | 3:1 | ||||
| 24. Round | 15/03/2018 | 1. FC Lok Leipzig | - | VSG Altglienicke | 2:0 | ||||
| 20. Round | 28/03/2018 | 1. FC Lok Leipzig | - | Union Fürstenwalde | 1:1 | ||||
| 25. Round | 04/04/2018 | FC Oberlausitz | - | 1. FC Lok Leipzig | 2:2 | ||||
| 26. Round | 02/05/2018 | 1. FC Lok Leipzig | - | TSG Neustrelitz | 7:0 | ||||
| 34. Round | 12/05/2018 | 1. FC Lok Leipzig | - | Hertha BSC II | 2:1 |
Germany