| 7. Round | 18/09/2021 | VfB 1921 Krieschow | - | 1. FC Merseburg | annull. | ||||
| 15. Round | 27/10/2021 | FSV Budissa Bautzen | - | VfB 1921 Krieschow | 1:2 | ||||
| 12. Round | 30/10/2021 | Inter Leipzig | - | VfB 1921 Krieschow | 2:1 | ||||
| 13. Round | 06/11/2021 | VfB 1921 Krieschow | - | Einheit Wernigerode | 4:0 | ||||
| 14. Round | 20/11/2021 | VfB 1921 Krieschow | - | FC Carl Zeiss Jena II | 6:0 | ||||
| 4. Round | 05/02/2022 | FC Einheit Rudolstadt | - | VfB 1921 Krieschow | 1:1 | ||||
| 17. Round | 26/02/2022 | Rot-Weiß Erfurt | - | VfB 1921 Krieschow | 5:0 | ||||
| 20. Round | 19/03/2022 | FSV Martinroda | - | VfB 1921 Krieschow | 0:3 | ||||
| 23. Round | 09/04/2022 | VfB 1921 Krieschow | - | FC Einheit Rudolstadt | 3:0 | ||||
| 24. Round | 16/04/2022 | Wacker Nordhausen | - | VfB 1921 Krieschow | 2:1 |  |
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| 16. Round | 18/04/2022 | VfB 1921 Krieschow | - | VFC Plauen | 2:2 | ||||
| 28. Round | 14/05/2022 | FC Oberlausitz | - | VfB 1921 Krieschow | 0:5 |
Germany