| 1. Round | 07/08/2016 | Arminia Bielefeld | - | Karlsruher SC | 0:0 | ||||
| 2. Round | 13/08/2016 | Karlsruher SC | - | VfL Bochum | 1:1 | ||||
| 3. Round | 27/08/2016 | Karlsruher SC | - | TSV 1860 München | 0:0 | ||||
| 4. Round | 10/09/2016 | 1. FC Union Berlin | - | Karlsruher SC | 4:0 | ||||
| 5. Round | 18/09/2016 | Karlsruher SC | - | FC St. Pauli | 1:1 | ||||
| 6. Round | 21/09/2016 | Hannover 96 | - | Karlsruher SC | 1:0 | ||||
| 18. Round | 29/01/2017 | Karlsruher SC | - | Arminia Bielefeld | 3:2 |
Guinea