| 1. Round | 14/08/2021 | TSV Emmelshausen | - | FC Karbach | 0:6 | ||||
| 2. Round | 21/08/2021 | FSV Salmrohr | - | TSV Emmelshausen | 1:2 | ||||
| 3. Round | 24/08/2021 | TSV Emmelshausen | - | TuS Koblenz | 0:2 | ||||
| 4. Round | 28/08/2021 | FV Engers 07 | - | TSV Emmelshausen | 0:0 | ||||
| 5. Round | 04/09/2021 | TSV Emmelshausen | - | SG Mülheim-Kärlich | 1:2 | ||||
| 6. Round | 11/09/2021 | TSV Emmelshausen | - | 1. FC Kaiserslautern II | 0:3 | ||||
| 7. Round | 17/09/2021 | SV Alemannia Waldalgesheim | - | TSV Emmelshausen | 2:0 | ||||
| 8. Round | 22/09/2021 | TSV Emmelshausen | - | Eintracht Trier | 0:5 | ||||
| 10. Round | 01/10/2021 | TSV Emmelshausen | - | Sportfreunde Eisbachtal | 2:0 | ||||
| 14. Round | 27/10/2021 | TuS Koblenz | - | TSV Emmelshausen | 1:1 | ||||
| 15. Round | 30/10/2021 | TSV Emmelshausen | - | FV Engers 07 | 0:2 | ||||
| 16. Round | 05/11/2021 | SG Mülheim-Kärlich | - | TSV Emmelshausen | 3:2 | ||||
| 17. Round | 13/11/2021 | 1. FC Kaiserslautern II | - | TSV Emmelshausen | 2:1 | ||||
| 18. Round | 20/11/2021 | TSV Emmelshausen | - | SV Alemannia Waldalgesheim | 1:2 | ||||
| 19. Round | 24/11/2021 | Eintracht Trier | - | TSV Emmelshausen | 5:0 | ||||
| 20. Round | 27/11/2021 | TSV Emmelshausen | - | Hassia Bingen | 1:0 |
Guinea