| 1. Round | 14/08/2022 | SpVgg Vreden | - | SV Schermbeck | 4:3 | ||||
| 4. Round | 04/09/2022 | FC Gütersloh | - | SpVgg Vreden | 3:1 | ||||
| 5. Round | 11/09/2022 | SpVgg Vreden | - | 1. FC Gievenbeck | 1:3 | ||||
| 7. Round | 25/09/2022 | SpVgg Vreden | - | FCE Rheine | 4:0 | ||||
| 9. Round | 09/10/2022 | SpVgg Vreden | - | TuS Ennepetal | 4:1 | ||||
| 11. Round | 23/10/2022 | SpVgg Vreden | - | TSG Sprockhövel | 2:1 | ||||
| 13. Round | 06/11/2022 | SpVgg Vreden | - | Viktoria Clarholz | 0:2 | ||||
| 15. Round | 27/11/2022 | TuS Bövinghausen | - | SpVgg Vreden | 2:3 | ||||
| 16. Round | 04/12/2022 | SpVgg Vreden | - | Sportfreunde Siegen | 1:1 | ||||
| 17. Round | 10/12/2022 | ASC 09 Dortmund | - | SpVgg Vreden | 2:1 | ||||
| 18. Round | 05/02/2023 | SV Schermbeck | - | SpVgg Vreden | 1:4 | ||||
| 19. Round | 12/02/2023 | SpVgg Vreden | - | Preußen Münster II | 1:4 | ||||
| 31. Round | 07/05/2023 | SpVgg Vreden | - | TuS Erndtebrück | 5:2 | ||||
| 32. Round | 14/05/2023 | SpVgg Vreden | - | TuS Bövinghausen | 3:2 | ||||
| 33. Round | 21/05/2023 | Sportfreunde Siegen | - | SpVgg Vreden | 4:0 | ||||
| 34. Round | 26/05/2023 | SpVgg Vreden | - | ASC 09 Dortmund | 2:4 |
Germany