| 1. Round | 06/08/2011 | Rot-Weiss Essen | - | 1. FSV Mainz 05 II | 2:1 | ||||
| 2. Round | 12/08/2011 | 1. FC Köln II | - | Rot-Weiss Essen | 2:1 | ||||
| 5. Round | 31/08/2011 | Rot-Weiss Essen | - | SC Verl | 3:1 | ||||
| 11. Round | 15/10/2011 | Bayer Leverkusen II | - | Rot-Weiss Essen | 1:0 |  |
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| 15. Round | 20/11/2011 | SC 07 Idar-Oberstein | - | Rot-Weiss Essen | 2:1 | ||||
| 16. Round | 26/11/2011 | Rot-Weiss Essen | - | FC Schalke 04 II | 1:0 | ||||
| 17. Round | 03/12/2011 | Borussia Dortmund II | - | Rot-Weiss Essen | 0:1 | ||||
| 18. Round | 10/12/2011 | Rot-Weiss Essen | - | Fortuna Düsseldorf II | 3:1 | ||||
| 21. Round | 28/01/2012 | Rot-Weiss Essen | - | 1. FC Köln II | 3:4 | ||||
| 27. Round | 09/03/2012 | VfL Bochum II | - | Rot-Weiss Essen | 2:4 | ||||
| 29. Round | 24/03/2012 | 1. FC Kaiserslautern II | - | Rot-Weiss Essen | 1:2 | ||||
| 23. Round | 27/03/2012 | Rot-Weiss Essen | - | TuS Koblenz | 2:0 | |
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| 24. Round | 18/04/2012 | SC Verl | - | Rot-Weiss Essen | 2:1 | ||||
| 36. Round | 05/05/2012 | Rot-Weiss Essen | - | Borussia Dortmund II | 0:4 | |
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| 38. Round | 19/05/2012 | Rot-Weiss Essen | - | Fortuna Köln | 1:1 |
Germany