1. Round | 24/07/2021 | KV Oostende | - | Sporting Charleroi | 0:3 | ||||
2. Round | 31/07/2021 | Sporting Charleroi | - | Sint-Truidense VV | 0:0 | ||||
4. Round | 13/08/2021 | Sporting Charleroi | - | Royal Antwerp FC | 1:1 | ||||
5. Round | 22/08/2021 | SV Zulte Waregem | - | Sporting Charleroi | 2:2 | ||||
6. Round | 28/08/2021 | Sporting Charleroi | - | K Beerschot VA | 5:2 | ||||
7. Round | 12/09/2021 | KAA Gent | - | Sporting Charleroi | 2:3 | ||||
8. Round | 18/09/2021 | Sporting Charleroi | - | Club Brugge KV | 0:1 | ||||
9. Round | 26/09/2021 | Sporting Charleroi | - | KV Mechelen | 0:2 | ||||
12. Round | 22/10/2021 | RFC Seraing | - | Sporting Charleroi | 1:3 |