| 1. Round | 14/08/2021 | 1. FC 06 Erlensee | - | Hünfelder SV | 3:2 | ||||
| 3. Round | 28/08/2021 | SV 1910 Neuhof | - | Hünfelder SV | 0:2 | ||||
| 4. Round | 01/09/2021 | Hünfelder SV | - | 1. FC 06 Erlensee | 1:1 |  |
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| 7. Round | 15/09/2021 | SV Steinbach | - | Hünfelder SV | 1:1 | ||||
| 8. Round | 18/09/2021 | Hünfelder SV | - | KSV Baunatal | 1:2 | ||||
| 10. Round | 29/09/2021 | Hünfelder SV | - | SV 1910 Neuhof | 2:2 | ||||
| 11. Round | 02/10/2021 | SV Buchonia Flieden | - | Hünfelder SV | 0:2 | ||||
| 12. Round | 09/10/2021 | Hünfelder SV | - | FC Hanau 93 | 2:1 | ||||
| 14. Round | 23/10/2021 | Hünfelder SV | - | SG Barockstadt Fulda-Lehnerz | 2:2 | ||||
| 15. Round | 26/10/2021 | Eintracht Stadtallendorf | - | Hünfelder SV | 3:1 | ||||
| 17. Round | 06/11/2021 | Hünfelder SV | - | Bayern Alzenau | 0:4 | ||||
| 18. Round | 13/11/2021 | FC Hanau 93 | - | Hünfelder SV | 1:1 | ||||
| 19. Round | 20/11/2021 | Hünfelder SV | - | SV Buchonia Flieden | 3:4 | |
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| 21. Round | 04/12/2021 | KSV Baunatal | - | Hünfelder SV | 2:1 | ||||
| 22. Round | 11/12/2021 | Hünfelder SV | - | FSV Fernwald | 2:1 |
Germany