| 1. Round | 06/08/2004 | 1. FSV Mainz 05 II | - | SV Darmstadt 98 | 2:1 | ||||
| 4. Round | 28/08/2004 | Stuttgarter Kickers | - | 1. FSV Mainz 05 II | 0:2 | ||||
| 7. Round | 19/09/2004 | 1. FSV Mainz 05 II | - | VfR Aalen | 0:0 | ||||
| 8. Round | 25/09/2004 | Jahn Regensburg | - | 1. FSV Mainz 05 II | 1:1 | ||||
| 11. Round | 17/10/2004 | 1. FSV Mainz 05 II | - | SV Wehen-Taunusstein | 1:3 | ||||
| 14. Round | 05/11/2004 | Bayern München II | - | 1. FSV Mainz 05 II | 0:0 | ||||
| 15. Round | 14/11/2004 | 1. FSV Mainz 05 II | - | TSV 1860 München II | 2:0 | ||||
| 16. Round | 21/11/2004 | 1. FSV Mainz 05 II | - | Sportfreunde Siegen | 2:1 |  |
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| 17. Round | 27/11/2004 | Kickers Offenbach | - | 1. FSV Mainz 05 II | 0:1 |  |
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| 19. Round | 04/12/2004 | 1. FSV Mainz 05 II | - | 1. SC Feucht | 0:3 | ||||
| 18. Round | 11/12/2004 | SV Darmstadt 98 | - | 1. FSV Mainz 05 II | 3:0 |
Germany