| 23. Round | 23/03/2013 | 1. FC Köln II | - | Rot-Weiss Essen | 1:4 | ||||
| 24. Round | 26/03/2013 | Rot-Weiss Essen | - | Fortuna Köln | 0:1 | ||||
| 29. Round | 30/03/2013 | FC Kray | - | Rot-Weiss Essen | 0:0 | ||||
| 25. Round | 02/04/2013 | Fortuna Düsseldorf II | - | Rot-Weiss Essen | 1:1 | ||||
| 30. Round | 06/04/2013 | Rot-Weiss Essen | - | FC Schalke 04 II | 1:0 | ||||
| 27. Round | 09/04/2013 | VfB Hüls | - | Rot-Weiss Essen | 5:0 | ||||
| 31. Round | 13/04/2013 | SC Wiedenbrück | - | Rot-Weiss Essen | 1:4 | ||||
| 32. Round | 20/04/2013 | Rot-Weiss Essen | - | Viktoria Köln | 4:0 | ||||
| 33. Round | 27/04/2013 | MSV Duisburg II | - | Rot-Weiss Essen | 2:0 | ||||
| 34. Round | 04/05/2013 | Rot-Weiss Essen | - | Bor. Mönchengladbach II | 1:6 | ||||
| 35. Round | 07/05/2013 | VfL Bochum II | - | Rot-Weiss Essen | 1:1 |  |
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| 36. Round | 10/05/2013 | Rot-Weiss Essen | - | Wuppertaler SV | 1:2 | ||||
| 37. Round | 19/05/2013 | Sportfreunde Lotte | - | Rot-Weiss Essen | 1:0 |
Germany