| 6. Round | 06/10/2024 | VfB Stuttgart | - | 1899 Hoffenheim | 1:1 | ||||
| 9. Round | 02/11/2024 | 1899 Hoffenheim | - | FC St. Pauli | 0:2 | ||||
| 10. Round | 10/11/2024 | FC Augsburg | - | 1899 Hoffenheim | 0:0 | ||||
| 12. Round | 01/12/2024 | 1. FSV Mainz 05 | - | 1899 Hoffenheim | 2:0 | ||||
| 15. Round | 21/12/2024 | 1899 Hoffenheim | - | Bor. Mönchengladbach | 1:2 | ||||
| 19. Round | 26/01/2025 | 1899 Hoffenheim | - | Eintracht Frankfurt | 2:2 | ||||
| 20. Round | 02/02/2025 | Bayer Leverkusen | - | 1899 Hoffenheim | 3:1 | ||||
| 21. Round | 08/02/2025 | 1899 Hoffenheim | - | 1. FC Union Berlin | 0:4 | ||||
| 23. Round | 23/02/2025 | 1899 Hoffenheim | - | VfB Stuttgart | 1:1 | ||||
| 26. Round | 14/03/2025 | FC St. Pauli | - | 1899 Hoffenheim | 1:0 | ||||
| 27. Round | 29/03/2025 | 1899 Hoffenheim | - | FC Augsburg | 1:1 | ||||
| 28. Round | 05/04/2025 | RB Leipzig | - | 1899 Hoffenheim | 3:1 | ||||
| 29. Round | 12/04/2025 | 1899 Hoffenheim | - | 1. FSV Mainz 05 | 2:0 | ||||
| 31. Round | 26/04/2025 | 1899 Hoffenheim | - | Borussia Dortmund | 2:3 |
Czech Republic