| 1. Round | 30/08/1980 | TSG Bau Rostock | - | TSG Wismar | 4:1 |  |
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| 2. Round | 06/09/1980 | BSG Motor Wolgast | - | TSG Bau Rostock | 0:0 | ||||
| 3. Round | 13/09/1980 | TSG Bau Rostock | - | BSG KKW Greifswald | 2:1 | ||||
| 4. Round | 20/09/1980 | TSG Bau Rostock | - | SG Dynamo Schwerin | 4:0 | ||||
| 5. Round | 04/10/1980 | BSG Post Neubrandenburg | - | TSG Bau Rostock | 1:0 | ||||
| 6. Round | 07/10/1980 | TSG Bau Rostock | - | Chemie/Motor Veritas Wittenberge | 2:1 | |
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| 7. Round | 19/10/1980 | BSG Lok Anklam | - | TSG Bau Rostock | 0:0 | ||||
| 8. Round | 26/10/1980 | TSG Bau Rostock | - | ASG Vorwärts Stralsund | 0:2 | ||||
| 9. Round | 08/11/1980 | BSG Schiffahrt/Hafen Rostock | - | TSG Bau Rostock | 2:2 | ||||
| 12. Round | 29/11/1980 | TSG Wismar | - | TSG Bau Rostock | 3:2 | ||||
| 13. Round | 06/12/1980 | TSG Bau Rostock | - | BSG Motor Wolgast | 2:4 | ||||
| 14. Round | 12/12/1980 | BSG KKW Greifswald | - | TSG Bau Rostock | 2:0 |
Germany