| 1. Round | 08/03/1959 | BSG Chemie Zeitz | - | SC Lokomotive Leipzig | 1:2 | ||||
| 2. Round | 15/03/1959 | SC Lokomotive Leipzig | - | BSG Lokomotive Stendal | 0:0 | ||||
| 3. Round | 22/03/1959 | SC Lokomotive Leipzig | - | SC Turbine Erfurt | 2:1 | ||||
| 4. Round | 05/04/1959 | SC Aktivist Brieske-Senftenberg | - | SC Lokomotive Leipzig | 2:0 | ||||
| 8. Round | 25/04/1959 | SC Lokomotive Leipzig | - | BSG Motor Zwickau | 1:2 | ||||
| 10. Round | 31/05/1959 | SC Lokomotive Leipzig | - | Fortschritt Weißenfels | 3:1 | ||||
| 11. Round | 07/06/1959 | SC Einheit Dresden | - | SC Lokomotive Leipzig | 1:1 | ||||
| 12. Round | 14/06/1959 | SC Lokomotive Leipzig | - | ASK Vorwärts Berlin | 1:0 | ||||
| 13. Round | 04/07/1959 | SC Wismut Karl-Marx-Stadt | - | SC Lokomotive Leipzig | 3:0 | ||||
| 14. Round | 02/08/1959 | SC Lokomotive Leipzig | - | BSG Chemie Zeitz | 1:1 | ||||
| 19. Round | 11/10/1959 | SC Rotation Leipzig | - | SC Lokomotive Leipzig | 0:0 | ||||
| 20. Round | 18/10/1959 | SC Lokomotive Leipzig | - | SC Empor Rostock | 1:2 |  |
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| 21. Round | 25/10/1959 | BSG Motor Zwickau | - | SC Lokomotive Leipzig | 1:0 |
Germany