| 1. Round | 08/03/1959 | BSG Chemie Zeitz | - | SC Lokomotive Leipzig | 1:2 | ||||
| 2. Round | 15/03/1959 | SC Lokomotive Leipzig | - | BSG Lokomotive Stendal | 0:0 | ||||
| 3. Round | 22/03/1959 | SC Lokomotive Leipzig | - | SC Turbine Erfurt | 2:1 | ||||
| 4. Round | 05/04/1959 | SC Aktivist Brieske-Senftenberg | - | SC Lokomotive Leipzig | 2:0 | ||||
| 5. Round | 08/04/1959 | SC Motor Jena | - | SC Lokomotive Leipzig | 0:0 | ||||
| 6. Round | 12/04/1959 | SC Empor Rostock | - | SC Lokomotive Leipzig | 2:2 | ||||
| 7. Round | 19/04/1959 | SC Lokomotive Leipzig | - | SC Rotation Leipzig | 2:2 | ||||
| 8. Round | 25/04/1959 | SC Lokomotive Leipzig | - | BSG Motor Zwickau | 1:2 | ||||
| 9. Round | 10/05/1959 | SC Dynamo Berlin | - | SC Lokomotive Leipzig | 5:0 | ||||
| 12. Round | 14/06/1959 | SC Lokomotive Leipzig | - | ASK Vorwärts Berlin | 1:0 | ||||
| 13. Round | 04/07/1959 | SC Wismut Karl-Marx-Stadt | - | SC Lokomotive Leipzig | 3:0 | ||||
| 14. Round | 02/08/1959 | SC Lokomotive Leipzig | - | BSG Chemie Zeitz | 1:1 | ||||
| 15. Round | 09/08/1959 | BSG Lokomotive Stendal | - | SC Lokomotive Leipzig | 1:2 | ||||
| 16. Round | 23/08/1959 | SC Lokomotive Leipzig | - | SC Motor Jena | 2:1 |
Poland