| 1. Round | 24/07/2021 | TSV 1860 München | - | Würzburger Kickers | 1:0 | ||||
| 4. Round | 22/08/2021 | Würzburger Kickers | - | VfL Osnabrück | 1:1 | ||||
| 5. Round | 25/08/2021 | SC Freiburg II | - | Würzburger Kickers | 1:0 | ||||
| 7. Round | 04/09/2021 | MSV Duisburg | - | Würzburger Kickers | 2:0 | ||||
| 12. Round | 17/10/2021 | Viktoria Köln | - | Würzburger Kickers | 1:1 | ||||
| 13. Round | 23/10/2021 | Würzburger Kickers | - | Türkgücü München | annull. | ||||
| 16. Round | 21/11/2021 | FC Viktoria 1889 Berlin | - | Würzburger Kickers | 1:1 | ||||
| 33. Round | 08/04/2022 | Würzburger Kickers | - | 1. FC Kaiserslautern | 1:2 | ||||
| 35. Round | 23/04/2022 | Würzburger Kickers | - | FC Viktoria 1889 Berlin | 3:0 | ||||
| 36. Round | 30/04/2022 | SV Meppen | - | Würzburger Kickers | 2:4 |
Germany
Turkey