| 1. Round | 10/09/2000 | Bohemian FC | - | 1. FC Kaiserslautern | 1:3 | ||||
| 1. Round | 20/09/2000 | 1. FC Kaiserslautern | - | Bohemian FC | 0:1 | ||||
| 2. Round | 22/10/2000 | Iraklis Saloniki | - | 1. FC Kaiserslautern | 1:3 |  |
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| 2. Round | 08/11/2000 | 1. FC Kaiserslautern | - | Iraklis Saloniki | 2:3 | ||||
| 3. Round | 29/11/2000 | Rangers FC | - | 1. FC Kaiserslautern | 1:0 | ||||
| 3. Round | 06/12/2000 | 1. FC Kaiserslautern | - | Rangers FC | 3:0 | ||||
| Quarter-finals | 07/03/2001 | 1. FC Kaiserslautern | - | PSV Eindhoven | 1:0 | ||||
| Quarter-finals | 14/03/2001 | PSV Eindhoven | - | 1. FC Kaiserslautern | 0:1 | ||||
| Semi-finals | 05/04/2001 | CD Alavés | - | 1. FC Kaiserslautern | 5:1 | |
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| Semi-finals | 19/04/2001 | 1. FC Kaiserslautern | - | CD Alavés | 1:4 |
Germany
