| 28. Round | 28/02/2022 | Türkgücü München | - | 1. FC Saarbrücken | annull. | ||||
| 29. Round | 06/03/2022 | 1. FC Saarbrücken | - | SV Meppen | 1:0 | ||||
| 30. Round | 12/03/2022 | Eintracht Braunschweig | - | 1. FC Saarbrücken | 0:2 | ||||
| 31. Round | 19/03/2022 | 1. FC Saarbrücken | - | Hallescher FC | 2:1 | ||||
| 32. Round | 02/04/2022 | TSV 1860 München | - | 1. FC Saarbrücken | 1:1 | ||||
| 33. Round | 09/04/2022 | 1. FC Saarbrücken | - | Waldhof Mannheim | 0:0 | ||||
| 34. Round | 17/04/2022 | 1. FC Kaiserslautern | - | 1. FC Saarbrücken | 3:1 | ||||
| 35. Round | 23/04/2022 | 1. FC Saarbrücken | - | SC Verl | 1:2 | ||||
| 36. Round | 29/04/2022 | FC Viktoria 1889 Berlin | - | 1. FC Saarbrücken | 2:1 |
Germany