| 1. Round | 08/08/2010 | 1. FC Nürnberg II | - | Wormatia Worms | 1:0 | ||||
| 3. Round | 21/08/2010 | 1. FC Nürnberg II | - | SC Pfullendorf | 1:0 | ||||
| 7. Round | 10/09/2010 | SpVgg Weiden | - | 1. FC Nürnberg II | annull. | ||||
| 8. Round | 18/09/2010 | 1. FC Nürnberg II | - | 1899 Hoffenheim II | 1:2 | ||||
| 9. Round | 21/09/2010 | TSV 1860 München II | - | 1. FC Nürnberg II | 5:2 | ||||
| 10. Round | 25/09/2010 | 1. FC Nürnberg II | - | SV Wehen Wiesbaden II | 2:0 | ||||
| 11. Round | 01/10/2010 | SSV Ulm 1846 | - | 1. FC Nürnberg II | annull. | ||||
| 12. Round | 16/10/2010 | 1. FC Nürnberg II | - | SC Freiburg II | 3:0 | ||||
| 14. Round | 30/10/2010 | 1. FC Nürnberg II | - | Karlsruher SC II | 1:2 | ||||
| 15. Round | 06/11/2010 | SpVgg Greuther Fürth II | - | 1. FC Nürnberg II | 6:1 |
Germany