| 1. Round | 03/04/2022 | SC Union Nettetal | - | SC Velbert | 4:0 | ||||
| 2. Round | 10/04/2022 | SC Düsseldorf-West | - | SC Union Nettetal | 4:0 | ||||
| 4. Round | 24/04/2022 | DJK Teutonia St. Tönis | - | SC Union Nettetal | 1:4 |  |
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| 3. Round | 27/04/2022 | SC Union Nettetal | - | Cronenberger SC | 5:0 | ||||
| 5. Round | 30/04/2022 | 1. FC Mönchengladbach | - | SC Union Nettetal | 2:3 | ||||
| 7. Round | 15/05/2022 | SC Union Nettetal | - | FC Kray | 4:0 |  |
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| 8. Round | 22/05/2022 | SC Union Nettetal | - | FSV Duisburg | 2:1 | ||||
| 9. Round | 29/05/2022 | SC Union Nettetal | - | TV Jahn Hiesfeld | 4:0 | ||||
| 10. Round | 06/06/2022 | SC Union Nettetal | - | TuRU Düsseldorf | 0:4 | ||||
| 11. Round | 12/06/2022 | SC Union Nettetal | - | SpVgg Sterkrade-Nord | 2:3 |
Germany