| 1. Round | 22/08/2021 | TV Jahn Hiesfeld | - | FC Kray | 1:4 | ||||
| 2. Round | 29/08/2021 | FC Kray | - | SpVg Schonnebeck | 2:5 | ||||
| 3. Round | 05/09/2021 | Cronenberger SC | - | FC Kray | 2:2 | ||||
| 4. Round | 12/09/2021 | FC Kray | - | SC Union Nettetal | 3:2 | ||||
| 5. Round | 19/09/2021 | SC Düsseldorf-West | - | FC Kray | 1:0 | ||||
| 7. Round | 03/10/2021 | 1. FC Kleve | - | FC Kray | 4:4 | ||||
| 8. Round | 10/10/2021 | FC Kray | - | TSV Meerbusch | 0:4 | ||||
| 9. Round | 17/10/2021 | 1. FC Bocholt | - | FC Kray | 3:0 | ||||
| 10. Round | 24/10/2021 | FC Kray | - | SSVg Velbert | 0:3 | ||||
| 16. Round | 12/12/2021 | TuRU Düsseldorf | - | FC Kray | 2:0 | ||||
| 17. Round | 18/12/2021 | FC Kray | - | Germania Ratingen 04/19 | 1:4 | ||||
| 18. Round | 20/02/2022 | 1. FC Monheim | - | FC Kray | 3:0 | ||||
| 19. Round | 27/02/2022 | FC Kray | - | 1. FC Mönchengladbach | 3:2 | ||||
| 20. Round | 06/03/2022 | FSV Duisburg | - | FC Kray | 3:0 | ||||
| 21. Round | 23/03/2022 | FC Kray | - | VfB 03 Hilden | 2:4 | ||||
| 23. Round | 27/03/2022 | FC Kray | - | Sportfreunde Niederwenigern | 4:2 | ||||
| 22. Round | 30/03/2022 | SC Velbert | - | FC Kray | 2:4 |
Germany