| 13. Round | 05/03/2022 | Wuppertaler SV [Youth] | - | Bor. Mönchengladbach [Youth] | 1:1 | ||||
| 14. Round | 03/04/2022 | VfL Bochum [Youth] | - | Wuppertaler SV [Youth] | 3:0 | ||||
| 15. Round | 09/04/2022 | Wuppertaler SV [Youth] | - | Preußen Münster [Youth] | 0:3 | ||||
| 16. Round | 23/04/2022 | Rot-Weiss Essen [Youth] | - | Wuppertaler SV [Youth] | 2:1 | ||||
| 17. Round | 30/04/2022 | Wuppertaler SV [Youth] | - | Rot-Weiß Oberhausen [Youth] | 4:1 |
Germany