| 1. Round | 15/08/2021 | FC Pesch 1956 | - | SV Breinig | 5:0 |  |
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| 2. Round | 19/08/2021 | BC Viktoria Glesch-Paffendorf | - | FC Pesch 1956 | 1:1 | ||||
| 3. Round | 22/08/2021 | FC Pesch 1956 | - | VfL 08 Vichttal | 3:0 | |
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| 4. Round | 29/08/2021 | FC Pesch 1956 | - | VfL Alfter | 1:1 | ||||
| 5. Round | 05/09/2021 | SV Deutz 05 | - | FC Pesch 1956 | 1:6 | |
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| 6. Round | 12/09/2021 | FC Pesch 1956 | - | 1. FC Düren | 1:2 | |
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| 7. Round | 17/09/2021 | Fortuna Köln II | - | FC Pesch 1956 | 1:1 | |
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| 12. Round | 24/10/2021 | FC Pesch 1956 | - | Blau-Weiß Friesdorf | 2:2 | |
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| 13. Round | 31/10/2021 | SV Bergisch Gladbach 09 | - | FC Pesch 1956 | 3:2 | |
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| 14. Round | 07/11/2021 | FC Pesch 1956 | - | SV 1914 Eilendorf | 3:1 | |
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| 15. Round | 14/11/2021 | Viktoria Arnoldsweiler | - | FC Pesch 1956 | 1:0 | ||||
| 16. Round | 28/11/2021 | FC Pesch 1956 | - | Siegburger SV 04 | 4:3 | |
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| 17. Round | 05/12/2021 | Spvg Wesseling-Urfeld | - | FC Pesch 1956 | 0:4 | |
Germany
Turkey