| 2. Round | 21/08/2021 | Erzgebirge Aue [Youth B] | - | FC Carl Zeiss Jena [Youth B] | 1:0 | ||||
| 5. Round | 19/09/2021 | Hannover 96 [Youth B] | - | Erzgebirge Aue [Youth B] | 2:1 | ||||
| 9. Round | 30/10/2021 | Erzgebirge Aue [Youth B] | - | RB Leipzig [Youth B] | 1:1 | ||||
| 10. Round | 06/11/2021 | FC St. Pauli [Youth B] | - | Erzgebirge Aue [Youth B] | 5:0 | ||||
| 11. Round | 20/11/2021 | Erzgebirge Aue [Youth B] | - | Energie Cottbus [Youth B] | 2:2 |
Germany