| 1. Round | 05/03/2022 | SV Buchonia Flieden | - | SV Zeilsheim | 1:0 | ||||
| 2. Round | 12/03/2022 | FV Bad Vilbel | - | SV Buchonia Flieden | 1:0 | ||||
| 3. Round | 19/03/2022 | SV Buchonia Flieden | - | Rot-Weiß Walldorf | 0:3 | ||||
| 4. Round | 27/03/2022 | VfB Ginsheim | - | SV Buchonia Flieden | 3:0 | ||||
| 5. Round | 16/04/2022 | SV Buchonia Flieden | - | Viktoria Griesheim | 0:3 | ||||
| 6. Round | 20/04/2022 | Türk Gücü Friedberg | - | SV Buchonia Flieden | 4:0 | ||||
| 7. Round | 23/04/2022 | SV Buchonia Flieden | - | FV Bad Vilbel | 2:1 |  |
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| 9. Round | 07/05/2022 | SV Buchonia Flieden | - | VfB Ginsheim | 0:2 |  |
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| 11. Round | 21/05/2022 | SV Buchonia Flieden | - | Türk Gücü Friedberg | 1:3 | ||||
| 12. Round | 29/05/2022 | SV Zeilsheim | - | SV Buchonia Flieden | 3:0 |
Germany