| 1. Round | 13/08/2022 | 1. FSV Mainz 05 [Youth] | - | 1899 Hoffenheim [Youth] | 4:0 |  |
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| 2. Round | 20/08/2022 | 1899 Hoffenheim [Youth] | - | SV Darmstadt 98 [Youth] | 3:1 | |
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| 3. Round | 27/08/2022 | FC Augsburg [Youth] | - | 1899 Hoffenheim [Youth] | 4:4 | ||||
| 4. Round | 04/09/2022 | 1899 Hoffenheim [Youth] | - | SC Freiburg [Youth] | 5:2 |  |
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| 11. Round | 04/12/2022 | 1899 Hoffenheim [Youth] | - | FC-Astoria Walldorf [Youth] | 7:0 | |
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| 12. Round | 04/02/2023 | VfB Stuttgart [Youth] | - | 1899 Hoffenheim [Youth] | 2:2 | ||||
| 13. Round | 11/02/2023 | 1899 Hoffenheim [Youth] | - | 1. FC Nürnberg [Youth] | 0:2 | ||||
| 14. Round | 18/02/2023 | Eintracht Frankfurt [Youth] | - | 1899 Hoffenheim [Youth] | 0:2 | |
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Germany