| 16. Round | 16/01/2021 | Erzgebirge Aue | - | Fortuna Düsseldorf | 0:3 |  |
|||
| 17. Round | 22/01/2021 | Fortuna Düsseldorf | - | SpVgg Greuther Fürth | 3:3 | ||||
| 19. Round | 29/01/2021 | Würzburger Kickers | - | Fortuna Düsseldorf | 2:1 | ||||
| 20. Round | 08/02/2021 | Fortuna Düsseldorf | - | Holstein Kiel | 0:2 | ||||
| 21. Round | 13/02/2021 | Jahn Regensburg | - | Fortuna Düsseldorf | 1:1 | ||||
| 22. Round | 21/02/2021 | Fortuna Düsseldorf | - | Hannover 96 | 3:2 |  |
|||
| 23. Round | 28/02/2021 | 1. FC Heidenheim 1846 | - | Fortuna Düsseldorf | 3:2 | ||||
| 26. Round | 22/03/2021 | Fortuna Düsseldorf | - | VfL Bochum | 0:3 | ||||
| 27. Round | 04/04/2021 | SV Darmstadt 98 | - | Fortuna Düsseldorf | 1:2 | ||||
| 29. Round | 18/04/2021 | VfL Osnabrück | - | Fortuna Düsseldorf | 0:3 | ||||
| 30. Round | 21/04/2021 | Fortuna Düsseldorf | - | FC St. Pauli | 2:0 | |
|||
| 31. Round | 24/04/2021 | SC Paderborn 07 | - | Fortuna Düsseldorf | 2:1 | ||||
| 28. Round | 03/05/2021 | Fortuna Düsseldorf | - | Karlsruher SC | 3:2 | ||||
| 32. Round | 08/05/2021 | Fortuna Düsseldorf | - | Eintracht Braunschweig | 2:2 | ||||
| 33. Round | 16/05/2021 | Fortuna Düsseldorf | - | Erzgebirge Aue | 3:0 | ||||
| 34. Round | 23/05/2021 | SpVgg Greuther Fürth | - | Fortuna Düsseldorf | 3:2 |
Germany