| 3. Round | 18/04/2022 | SpVgg Vreden | - | Hammer SpVg | 1:0 | ||||
| 2. Round | 28/04/2022 | TuS Ennepetal | - | SpVgg Vreden | 2:2 | ||||
| 5. Round | 01/05/2022 | SpVgg Vreden | - | Westfalia Herne | 5:0 |  |
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| 7. Round | 08/05/2022 | SpVgg Vreden | - | Preußen Münster II | 2:0 | ||||
| 8. Round | 15/05/2022 | SG Finnentrop/Bamenohl | - | SpVgg Vreden | 1:2 | ||||
| 1. Round | 19/05/2022 | SpVgg Vreden | - | Holzwickeder SC | 3:2 | ||||
| 9. Round | 22/05/2022 | TSG Sprockhövel | - | SpVgg Vreden | 0:0 | ||||
| 10. Round | 29/05/2022 | SpVgg Vreden | - | TuS Haltern | 7:2 | ||||
| 11. Round | 06/06/2022 | RSV Meinerzhagen | - | SpVgg Vreden | 1:0 |
Germany