| 17. Round | 20/02/2022 | SC Paderborn 07 II | - | 1. FC Kaan-Marienborn | 1:1 | ||||
| 18. Round | 06/03/2022 | 1. FC Kaan-Marienborn | - | RSV Meinerzhagen | 1:0 | ||||
| 19. Round | 13/03/2022 | Westfalia Herne | - | 1. FC Kaan-Marienborn | 2:5 | ||||
| 20. Round | 20/03/2022 | 1. FC Kaan-Marienborn | - | Westfalia Rhynern | 0:0 | ||||
| 21. Round | 07/04/2022 | Holzwickeder SC | - | 1. FC Kaan-Marienborn | 1:1 |
Germany