| 1. Round | 24/07/2010 | Wacker Burghausen | - | SV Sandhausen | 1:4 | ||||
| 2. Round | 31/07/2010 | SV Sandhausen | - | Kickers Offenbach | 0:2 | ||||
| 3. Round | 03/08/2010 | Eintracht Braunschweig | - | SV Sandhausen | 2:0 | ||||
| 4. Round | 07/08/2010 | SV Sandhausen | - | FC Carl Zeiss Jena | 0:2 | ||||
| 8. Round | 18/09/2010 | SV Sandhausen | - | VfB Stuttgart II | 0:1 | ||||
| 9. Round | 22/09/2010 | SV Sandhausen | - | Bayern München II | 1:0 | ||||
| 10. Round | 25/09/2010 | SV Wehen Wiesbaden | - | SV Sandhausen | 2:0 | ||||
| 11. Round | 02/10/2010 | SV Sandhausen | - | Jahn Regensburg | 2:2 | ||||
| 12. Round | 16/10/2010 | Rot Weiss Ahlen | - | SV Sandhausen | 1:1 | ||||
| 13. Round | 23/10/2010 | SV Sandhausen | - | VfR Aalen | 1:3 | ||||
| 14. Round | 30/10/2010 | Rot-Weiß Erfurt | - | SV Sandhausen | 2:1 | ||||
| 15. Round | 05/11/2010 | SV Sandhausen | - | Hansa Rostock | 1:2 | ||||
| 16. Round | 14/11/2010 | TuS Koblenz | - | SV Sandhausen | 3:0 | ||||
| 17. Round | 20/11/2010 | SV Sandhausen | - | Werder Bremen II | 5:1 | ||||
| 18. Round | 28/11/2010 | SpVgg Unterhaching | - | SV Sandhausen | 1:1 | ||||
| 19. Round | 07/12/2010 | SV Sandhausen | - | SV Babelsberg 03 | 0:0 |
Germany