| 2. Round | 21/08/2021 | FC Hertha Wiesbach | - | Arminia Ludwigshafen | 2:2 | ||||
| 3. Round | 25/08/2021 | SV 07 Elversberg II | - | FC Hertha Wiesbach | 2:4 | ||||
| 4. Round | 28/08/2021 | FC Hertha Wiesbach | - | SV Röchling Völklingen | 2:1 | ||||
| 5. Round | 04/09/2021 | FV Eppelborn | - | FC Hertha Wiesbach | 1:3 | ||||
| 6. Round | 11/09/2021 | FC Hertha Wiesbach | - | TuS Mechtersheim | 3:2 | ||||
| 8. Round | 22/09/2021 | FC Hertha Wiesbach | - | FV Dudenhofen | 3:2 | ||||
| 11. Round | 10/10/2021 | FC Speyer 09 | - | FC Hertha Wiesbach | 1:2 | ||||
| 12. Round | 16/10/2021 | FC Hertha Wiesbach | - | Wormatia Worms | 1:2 | ||||
| 15. Round | 31/10/2021 | SV Röchling Völklingen | - | FC Hertha Wiesbach | 0:1 | ||||
| 17. Round | 13/11/2021 | TuS Mechtersheim | - | FC Hertha Wiesbach | 2:2 | ||||
| 18. Round | 20/11/2021 | FC Hertha Wiesbach | - | TSG Pfeddersheim | 3:2 | ||||
| 20. Round | 27/11/2021 | FC Hertha Wiesbach | - | FSV Jägersburg | 4:1 | ||||
| 16. Round | 09/03/2022 | FC Hertha Wiesbach | - | FV Eppelborn | 6:0 |
Germany