| 1. Round | 22/08/1981 | HFC Chemie | - | 1. FC Lokomotive Leipzig | 1:1 | ||||
| 2. Round | 29/08/1981 | FC Karl-Marx-Stadt | - | HFC Chemie | 2:1 | ||||
| 8. Round | 24/10/1981 | BSG Wismut Aue | - | HFC Chemie | 4:1 |  |
|||
| 9. Round | 31/10/1981 | HFC Chemie | - | BSG Energie Cottbus | 2:1 | ||||
| 10. Round | 14/11/1981 | Dynamo Dresden | - | HFC Chemie | 1:0 | ||||
| 11. Round | 28/11/1981 | HFC Chemie | - | 1. FC Magdeburg | 2:2 | ||||
| 12. Round | 06/12/1981 | BFC Dynamo | - | HFC Chemie | 5:1 | ||||
| 13. Round | 19/12/1981 | HFC Chemie | - | FC Carl Zeiss Jena | 2:1 | ||||
| 16. Round | 06/03/1982 | Hansa Rostock | - | HFC Chemie | 2:0 | ||||
| 17. Round | 13/03/1982 | HFC Chemie | - | FC Vorwärts Frankfurt/Oder | 0:2 | ||||
| 18. Round | 20/03/1982 | Rot-Weiß Erfurt | - | HFC Chemie | 0:0 | ||||
| 19. Round | 03/04/1982 | HFC Chemie | - | BSG Chemie Buna Schkopau | 1:1 | ||||
| 20. Round | 10/04/1982 | BSG Sachsenring Zwickau | - | HFC Chemie | 0:0 | ||||
| 21. Round | 17/04/1982 | HFC Chemie | - | BSG Wismut Aue | 3:0 | ||||
| 22. Round | 24/04/1982 | BSG Energie Cottbus | - | HFC Chemie | 2:0 | ||||
| 24. Round | 15/05/1982 | 1. FC Magdeburg | - | HFC Chemie | 3:0 | ||||
| 26. Round | 29/05/1982 | FC Carl Zeiss Jena | - | HFC Chemie | 1:2 |
Germany