| 1. Round | 30/08/1980 | BSG MK Sangerhausen | - | BSG Chemie Buna Schkopau | 1:3 | ||||
| 2. Round | 06/09/1980 | BSG Chemie Buna Schkopau | - | Chemie Schönebeck | 2:1 | ||||
| 3. Round | 13/09/1980 | BSG Stahl Nordwest Leipzig | - | BSG Chemie Buna Schkopau | 1:3 | ||||
| 4. Round | 20/09/1980 | BSG Chemie Buna Schkopau | - | ASG Vorwärts Dessau | 2:0 | ||||
| 5. Round | 04/10/1980 | BSG Chemie Leipzig | - | BSG Chemie Buna Schkopau | 3:1 | ||||
| 6. Round | 07/10/1980 | BSG Chemie Buna Schkopau | - | BSG Stahl Thale | 1:1 | ||||
| 7. Round | 19/10/1980 | SG Dynamo Eisleben | - | BSG Chemie Buna Schkopau | 6:1 | ||||
| 8. Round | 26/10/1980 | BSG Chemie Wolfen | - | BSG Chemie Buna Schkopau | 0:1 | ||||
| 17. Round | 14/03/1981 | BSG Stahl Thale | - | BSG Chemie Buna Schkopau | 1:1 | ||||
| 22. Round | 16/04/1981 | BSG Stahl Blankenburg | - | BSG Chemie Buna Schkopau | 2:2 |
Germany