| 1. Round | 27/08/1950 | Fortuna Düsseldorf | - | Preußen Dellbrück | 1:1 |  |
|||
| 2. Round | 03/09/1950 | Preußen Dellbrück | - | Duisburger SpV | 1:0 | ||||
| 3. Round | 10/09/1950 | Borussia Dortmund | - | Preußen Dellbrück | 3:2 | |
|||
| 4. Round | 17/09/1950 | Preußen Dellbrück | - | Rheydter SV | 1:2 | ||||
| 5. Round | 24/09/1950 | DJK SF Katernberg | - | Preußen Dellbrück | 0:2 | |
|||
| 6. Round | 01/10/1950 | Preußen Dellbrück | - | Rot-Weiß Oberhausen | 2:0 | |
|||
| 7. Round | 08/10/1950 | 1. FC Köln | - | Preußen Dellbrück | 1:0 | ||||
| 8. Round | 15/10/1950 | Preußen Dellbrück | - | FC Schalke 04 | 1:1 | ||||
| 9. Round | 22/10/1950 | Preußen Dellbrück | - | Alemannia Aachen | 3:3 | |
|||
| 10. Round | 29/10/1950 | SpVgg Erkenschwick | - | Preußen Dellbrück | 1:0 | ||||
| 11. Round | 05/11/1950 | Preußen Dellbrück | - | SF Hamborn 07 | 3:2 | ||||
| 12. Round | 12/11/1950 | Borussia VfL M.-Gladbach | - | Preußen Dellbrück | 3:3 | |
|||
| 13. Round | 19/11/1950 | Preußen Dellbrück | - | Rot-Weiss Essen | 2:3 | |
|||
| 14. Round | 26/11/1950 | STV Horst-Emscher | - | Preußen Dellbrück | 4:1 | ||||
| 15. Round | 03/12/1950 | Preußen Münster | - | Preußen Dellbrück | 2:1 | |
Germany