| 1. Round | 30/08/1980 | Chemie Schönebeck | - | SG Dynamo Eisleben | 0:5 |  |
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| 2. Round | 06/09/1980 | SG Dynamo Eisleben | - | BSG Stahl Nordwest Leipzig | 1:1 | |
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| 3. Round | 13/09/1980 | ASG Vorwärts Dessau | - | SG Dynamo Eisleben | 0:1 | ||||
| 15. Round | 28/02/1981 | SG Dynamo Eisleben | - | BSG Chemie Leipzig | 0:1 | ||||
| 16. Round | 07/03/1981 | SG Dynamo Eisleben | - | BSG Stahl Thale | 5:0 | ||||
| 17. Round | 14/03/1981 | SG Dynamo Eisleben | - | BSG Chemie Wolfen | 2:2 | ||||
| 19. Round | 28/03/1981 | SG Dynamo Eisleben | - | BSG Lokomotive Stendal | 1:1 | ||||
| 20. Round | 03/04/1981 | BSG Chemie Zeitz | - | SG Dynamo Eisleben | 1:0 |
Germany