| 2. Round | 03/09/1950 | Preußen Dellbrück | - | Duisburger SpV | 1:0 | ||||
| 4. Round | 17/09/1950 | SpVgg Erkenschwick | - | Duisburger SpV | 2:0 | ||||
| 5. Round | 24/09/1950 | Duisburger SpV | - | STV Horst-Emscher | 0:2 | ||||
| 6. Round | 01/10/1950 | Borussia VfL M.-Gladbach | - | Duisburger SpV | 0:1 | ||||
| 7. Round | 08/10/1950 | Duisburger SpV | - | Alemannia Aachen | 1:2 | ||||
| 12. Round | 12/11/1950 | Borussia Dortmund | - | Duisburger SpV | 0:0 | ||||
| 13. Round | 19/11/1950 | Fortuna Düsseldorf | - | Duisburger SpV | 4:0 | ||||
| 14. Round | 26/11/1950 | Duisburger SpV | - | Rheydter SV | 0:0 | ||||
| 20. Round | 04/02/1951 | STV Horst-Emscher | - | Duisburger SpV | 3:0 | ||||
| 25. Round | 11/03/1951 | Duisburger SpV | - | FC Schalke 04 | 2:2 |  |
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| 26. Round | 18/03/1951 | DJK SF Katernberg | - | Duisburger SpV | 5:2 | ||||
| 27. Round | 01/04/1951 | Duisburger SpV | - | Borussia Dortmund | 3:2 | ||||
| 28. Round | 08/04/1951 | Duisburger SpV | - | Fortuna Düsseldorf | 1:1 | ||||
| 29. Round | 22/04/1951 | Rheydter SV | - | Duisburger SpV | 3:1 |
Germany