| 1. Round | 29/08/1980 | 1. FC Union Berlin | - | Dynamo Fürstenwalde | 3:1 | ||||
| 3. Round | 13/09/1980 | BSG Halbleiterwerk Frankfurt (Oder) | - | 1. FC Union Berlin | 0:2 | ||||
| 4. Round | 19/09/1980 | 1. FC Union Berlin | - | BSG Chemie PCK Schwedt | 1:2 | ||||
| 5. Round | 04/10/1980 | BSG Stahl Hennigsdorf | - | 1. FC Union Berlin | 2:6 | ||||
| 6. Round | 07/10/1980 | 1. FC Union Berlin | - | Motor Hennigsdorf | 7:1 | ||||
| 7. Round | 18/10/1980 | BSG Bergmann Borsig | - | 1. FC Union Berlin | 1:1 | ||||
| 14. Round | 12/12/1980 | 1. FC Union Berlin | - | BSG Halbleiterwerk Frankfurt (Oder) | 4:0 | ||||
| 19. Round | 27/03/1981 | KWO Berlin | - | 1. FC Union Berlin | 3:0 | ||||
| 20. Round | 03/04/1981 | 1. FC Union Berlin | - | BSG Motor Süd Brandenburg | 1:0 | ||||
| 21. Round | 10/04/1981 | BSG Stahl Brandenburg | - | 1. FC Union Berlin | 2:1 | ||||
| 22. Round | 16/04/1981 | 1. FC Union Berlin | - | BSG Motor Eberswalde | 3:0 |
Germany